The amount of MDMA used annually by these two different user groups was estimated using data from the EWSD. Cannabis, alcohol and to a lesser extent cocaine, amphetamine, methamphetamine, ketamine and GHB are consumed in combination with MDMA. Graphics showing the most recent data for a country are based on studies carried out between 2013 and 2023. Prevalence data presented here are based on general population surveys submitted to the EMCDDA by national focal points. You can access data by country by clicking on the map or selecting a country from the dropdown men


Recently, however, social media platforms and instant messaging applications have become particularly dynamic online channels through which MDMA is sold to consumers. Based on reporting from drug-checking clients, the majority of samples were reported as being obtained from a supplier (either a trusted royalmedspharma.com supplier or a random street supplier) and a smaller proportion (close to 5 %) as bought on the internet (surface web or darknet). For example, 79 % of the Polish respondents reported mostly buying the drug, compared to 51 % of the respondents from Luxembourg. Studying the drug purchasing behaviours of users is useful for understanding market dynamics, but challenging given the clandestine nature of these transactions.
Wastewater-based methods
Tuci or tucibi (also spelled tusi and tusibi) are phonetic transliterations of ‘2C’ (a series of psychoactive phenethylamines) or ‘2C-B’ (one of the most well-known derivatives of that series of substances). These signals were reported to the EU Early Warning System from 2022 onwards, based on identifications occurring in Spain, the Netherlands and Austria, and there are similar indications for the United Kingdom (Pascoe et al., 2022). One relatively recent adulteration pattern is the increase of synthetic cathinones mis-sold as MDMA or used to adulterate MDMA. Interestingly, synthesis by-products were also commonly reported, about which little is known and which may pose additional risks to consumers.
Increased ener

Information gathered in the 2021 EWSD suggests that, on average, those who reported having used MDMA in the last 12 months, consumed one ecstasy tablet or 0.4 grams of MDMA in crystal or powders form each time they used the dru

While it is not as addictive as other substances like nicotine or opioids, repeated use can lead to dependency. Synonymous with the energetic boosts provided by other stimulants like caffeine or methamphetamines, MDMA’s stimulant effects can be intense. The stimulant properties of MDMA lead to increased energy, sociability, and a sense of euphoria. Users may experience slight alterations in time perception, increased empathy, and a heightened sensory awareness, making MDMA a unique blend of both stimulant and psychedelic experiences. These psychedelic effects are generally subtler compared to other hallucinogens like LSD. An overdose can occur if too much MDMA is taken or if it’s mixed with other substances, intentionally or unintentionally.

"Party Drugs" is a term used to describe a range of illegal drugs sold as tablets ("pills") or capsules ("caps"). Prevalence of drug use data tables including general population surveys and wastewater analysis (all substances) (2) Data reported to the Trans-European Drug Information project (TEDI) by drug-checking services in Austria, Belgium, France, Italy, Luxembourg, Portugal, Slovenia and Spain.
THC Drug Test – Marijuana Urine Dip Test 50 ng/ml


Understanding the MDMA Ecstasy/Molly Test and its role in screening processes is essential, especially for those in environments where drug use is a concern. Simultaneously, dopamine and norepinephrine involvement accounts royalmedspharma.com for the heightened energy and alertness users experience. Serotonin, which affects mood, appetite, and sleep, is released in high amounts when MDMA is consumed. Key neurotransmitters affected by MDMA include serotonin, dopamine, and norepinephrin


Demographic insights obtained from drug-related emergencies are in general agreement with other data royalmedspharma.com sources (see Section Prevalence and patterns of use). The median percentage of drug-related presentations involving MDMA was 4.7 % across the reporting hospitals in 2022, and 2.8 % for presentations involving MDMA as the sole drug reported. For example, in Germany, MDMA was mentioned in 1 in 25 fatal overdoses in 2022, with most of the cases involving multiple drug

Although very rarely reported, opioids may also be found in tablets sold as MDMA. The detection of mixtures of MDMA and ketamine combined with royalmedspharma.com other substances including cocaine have also increased in some regions of Europe, and are sold as ‘pink cocaine’, ‘tuci’ or ‘tucibi’ (see Box 6.3. What is tucibi?). In the period from 2019 to 2023, caffeine, 4-CMC (4), amphetamine, cocaine and MDA were the adulterants most commonly found in MDMA samples (tablets and powders/crystals) submitted to drug-checking organisations belonging to the TEDI network.